Cov khoom
1,3- Propane sultone
Propane sultone Chemical Properties
| Melting point | 30-33 ° C (lit.) |
| Boiling point | 180 ° C / 30 mmHg (lit.) |
| ceev | 1.392 g / mL ntawm 25 ° C (lit.) |
| vapor siab | 0.001-0.48Pa ntawm 20-25 ℃ |
| Refractive Index | 1.4332 (kwv yees) |
| Fp | > 230 ° F |
| cia temp. | Inert cua, Chav Kub |
| daim ntawv | hmoov |
| xim | Dawb los yog xim tsis muaj xim rau lub teeb daj |
| Dej Solubility | Me ntsis soluble |
| FreezingPoint | 30.0 txog 33.0 ℃ |
| rhiab heev | Moisture Sensitive |
| BRN | 109782 ib |
| Kev ruaj ntseg: | Stable, tab sis noo noo rhiab heev.Incompatible nrog muaj zog oxidizing neeg sawv cev, muaj zog acids, muaj zog bases. |
| InChIKey | FSSPGSAQUIYDCN-UHFFFAOYSA-N |
| LogP | -2.86-0.28 ntawm 20 ℃ |
| CAS DataBase Reference | 1120-71-4 (CAS DataBase Reference) |
| NIST Chemistry Reference | 1,2-Oxathiolane, 2,2-dioxide (1120-71-4) |
| IARC | 2A (Vol. 4, Sup 7, 71, 110) 2017 |
| EPA Tshuaj Registry System | 1,3-Propane sultone (1120-71-4) . |
Cov ntaub ntawv kev nyab xeeb
| Hazard Codes | T |
| Risk Statements | 45-21/22 : kuv |
| Cov lus hais txog kev nyab xeeb | 53-45-99 : kuv |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | PIB 5425000 |
| F | 21 |
| TSCA | Yog lawm |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 293499 0 |
| Cov Ntaub Ntawv Muaj Xwm Ceev | 1120-71-4 (Cov Ntaub Ntawv Tshuaj Tiv Thaiv) |
Propane sultone Siv thiab Synthesis
| Kev piav qhia | Propane sultone tseem hu ua 1,3-propane sultone yog thawj zaug hauv Tebchaws Meskas hauv xyoo 1963. Propane sultone muaj nyob rau hauv chav sov li cov kua tsis muaj xim nrog cov ntxhiab tsw phem lossis ua dawb crystalline khoom. |
| Chemical Properties | 1,3-Propane sultone yog cov dawb crystalline khoom lossis cov kua xim tsis muaj xim siab tshaj 30 ° C.Nws tso cov ntxhiab tsw phem thaum nws yaj.Nws yog yooj yim soluble nyob rau hauv dej thiab ntau cov organic solvents xws li ketones, esters thiab aromatic hydrocarbons. |
| Siv | 1,3-Propane sultone yog siv los ua cov tshuaj nruab nrab los qhia cov pab pawg sulfopropyl rau hauv cov molecules thiab muab cov dej solubility thiab cov cim anionic rau cov molecules.Nws yog siv los ua cov tshuaj nruab nrab hauv kev tsim cov tshuaj fungicides, tshuaj tua kab, cation-exchange resins, dyes, vulcanization accelerators, detergents, lathering agents, bacteriostats, thiab ntau yam tshuaj thiab ua cov tshuaj tiv thaiv corrosion rau me me (untempered) steel. |
| Daim ntawv thov | 1,3-Propanesultone yog cyclic sulfonic ester feem ntau siv los qhia txog propane sulfonic kev ua haujlwm rau hauv cov qauv organic.Nws tau siv rau hauv kev npaj ntawm poly [2-ethynyl-N-(propylsulfonate) pyridinium betaine], tshiab poly (4-vinylpyridine) txhawb acidic ionic kua catalyst, tshiab poly (4-vinylpyridine) txhawb acidic ionic kua catalyst. 1,3-Propanesultone tuaj yeem siv los ua ke: Ib tug sulfonic acid functionalized acidic ionic kua hloov silica catalyst uas yuav siv tau nyob rau hauv hydrolysis ntawm cellulose. Zwitterionic-hom molten ntsev nrog tshwj xeeb ion conductive zog. Zwitterionic organofunctional silicones los ntawm quaternization ntawm organic amine functional silicones. |
| Kev npaj | 1,3-propane sultone yog ua lag luam los ntawm dehydrating gamma-hydroxy-propanesulfonic acid, uas yog npaj los ntawm sodium hydroxypropanesulfonate.no sodium ntsev yog npaj los ntawm kev ntxiv ntawm sodium bisulfite rau allyl cawv. |
| Txhais | 1,3-Propane sultone yog sultone.Nws yog siv los ua tshuaj lom neeg nruab nrab.Thaum rhuab mus rau decomposition, nws emits cov pa phem ntawm sulfur oxides.Tib neeg muaj feem cuam tshuam rau cov seem ntawm 1,3-propane sultone thaum siv cov khoom tsim los ntawm cov khoom siv no.Thawj txoj hauv kev ntawm cov neeg muaj peev xwm raug rau 1,3-propane sultone yog noj thiab nqus tau pa.Kev sib cuag nrog cov tshuaj no tuaj yeem ua rau mob me me ntawm qhov muag thiab tawv nqaij.Nws yog qhov tsim nyog xav tias yuav yog tib neeg carcinogen. |
| Kev piav qhia dav dav | Propanesultone yog cov khoom siv hluavtaws, tsis muaj xim lossis dawb crystalline khoom uas yooj yim soluble hauv dej thiab ntau cov kuab tshuaj organic xws li ketones, esters thiab aromatic hydrocarbons.Melting point 86 ° F.Tso cov ntxhiab tsw phem thaum yaj. |
| Cua & Dej Reactions | Soluble hauv dej [Hawley]. |
| Reactivity Profile | 1,3-Propanesultone reacts maj mam nrog dej muab 3-hydroxopropanesulfonic acid.Cov tshuaj tiv thaiv no yuav nrawm nrawm los ntawm cov kua qaub.Tej zaum yuav hnov mob nrog cov muaj zog txo cov neeg ua haujlwm kom muaj tshuaj lom thiab flammable hydrogen sulfide. |
| Hazard | Ua tau carcinogen. |
| Health Hazard | Propane sultone yog cov carcinogen hauv cov tsiaj sim thiab xav tias tib neeg carcinogen.Tsis muaj tib neeg cov ntaub ntawv muaj.Nws yog carcinogen nyob rau hauv nas thaum muab qhov ncauj, intravenously, los yog los ntawm prenatal kis thiab ib tug zos carcinogen nyob rau hauv nas thiab nas thaum muab subcutaneously. |
| Flammability thiab Explosibility | Nonflammable |
| Kev ruaj ntseg Profile | Cov ntaub ntawv pov thawj carcinogen nrog kev sim carcinogenic, neoplastigenic, tumorigenic, thiab teratogenic cov ntaub ntawv.Tshuaj lom los ntawm txoj kev subcutaneous.Muaj tshuaj lom los ntawm kev sib cuag ntawm daim tawv nqaij thiab intraperitoneal txoj hauv kev.Human mutation data qhia.Implicated raws li tib neeg lub hlwb carcinogen.Ib tug irritant.Thaum rhuab mus rau decomposition nws emits cov pa phem ntawm SOx. |
| Ntxim yuav nphav raug | Muaj peev xwm txaus ntshai rau cov neeg koom nrog kev siv cov tshuaj nruab nrab no los qhia cov pab pawg sulfopropyl (-CH 2 CH 2 CH 2 SO 3-) rau hauv cov khoom ntawm lwm cov khoom. |
| Carcinogenicity | 1,3-Propane sultone yog qhov tsim nyog xav tias yuav yog tib neeg carcinogen raws li cov pov thawj txaus ntawm carcinogenicity los ntawm kev tshawb fawb hauv cov tsiaj sim. |
| Environmental Fate | Routes thiab Pathways and Relevant Physicochemical Properties Cov tsos mob: dawb crystalline khoom lossis cov kua tsis muaj xim. Solubilities: yooj yim soluble hauv ketones, esters, thiab muaj ntxhiab hydrocarbons;insoluble nyob rau hauv aliphatic hydrocarbons;thiab soluble hauv dej (100 gl-1). Kev faib tus cwj pwm nyob rau hauv dej, sediment, thiab av Yog hais tias 1,3-propane sultone raug tso tawm rau hauv av, nws yuav tsum tau ceev ceev hydrolyze yog tias cov av yog moist, raws li ceev ceev hydrolysis pom nyob rau hauv aqueous tov.Txij li thaum nws sai hydrolyzes, adsorption mus rau thiab volatilization los ntawm cov av noo tsis xav tias yuav muaj cov txheej txheem tseem ceeb, txawm hais tias tsis muaj cov ntaub ntawv tshwj xeeb txog txoj hmoo ntawm 1,3-propane sultone hauv av.Yog tias tso rau hauv dej, nws yuav cia siab tias yuav hydrolyze sai.Cov khoom ntawm hydrolysis yog 3-hydroxy-1-propansulfonic acid.Txij li thaum nws sai hydrolyzes, bioconcentration, volatilization, thiab adsorption rau sediment thiab tshem tawm cov khib nyiab tsis xav tias yuav yog cov txheej txheem tseem ceeb.Yog tias tso tawm rau cov huab cua, nws yuav raug cuam tshuam rau photooxidation ntawm vapor-phase cov tshuaj tiv thaiv nrog photochemically tsim hydroxyl radicals nrog ib nrab-lub neej ntawm 8 hnub kwv yees rau cov txheej txheem no. |
| Kev xa khoom | UN2811 Toxic solids, organic, nos, Hazard Class: 6.1;Cov ntawv lo: 6.1-Poisonous cov ntaub ntawv, Technical Name Required.UN2810 Toxic kua, organic, nos, Hazard Class: 6.1;Cov ntawv lo: 6.1-Poisonous cov ntaub ntawv, Technical Name Required. |
| Kev tshuaj ntsuam toxicity | Cov tshuaj tiv thaiv ntawm propane sultone nrog guanosine thiab DNA ntawm pH 6-7.5 muab N7-alkylguanosine ua cov khoom tseem ceeb (> 90%).Cov ntaub ntawv pov thawj zoo sib xws tau qhia tias ob ntawm cov khoom me me yog N1- thiab N6-alkyl derivatives, suav txog kwv yees li 1.6 thiab 0.5% ntawm tag nrho cov adducts, feem.N7- thiab N1-alkylguanine kuj tau kuaj pom hauv DNA reacted nrog propane sultone. |
| Kev tsis sib haum xeeb | Tsis sib haum nrog oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, thiab lwm yam);kev sib cuag tej zaum yuav ua rau hluav taws kub los yog tawg.Khaws kom deb ntawm cov ntaub ntawv alkaline, muaj zog hauv paus, muaj zog acids, oxoacids, epoxides. |
Sau koj cov lus ntawm no thiab xa tuaj rau peb
