Cov khoom
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Cov ntsiab lus: 4(1H)-Pyrimidinone, 2,6-diamino- (8CI,9CI); 2,4-Diamino-6-hydroxypyrimidine; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-3,4 -dihydropyrimidin-4-one; 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diamino-4(3H)-pyrimidinone; 2,6-Diamino-4-hydroxypyrimidine; 2,6-Diamino-4 -pyrimidinol; 2,6-Diaminopyrimidin-4-one; 2,6-Diaminopyrimidine-4(3H)-ib; 6-Aminoisocytosine; 6-Hydroxy-2,4-pyrimidinediamine; NSC 44914; NSC 680818; NSC9302;
Cov cuab yeej tshuaj ntawm 2,4-Diamino-6-hydroxypyrimidine
● Cov tsos / Xim: dawb khoom
● Vapor Pressure: 0.00232mmHg ntawm 25 ° C
● Melting Point: 285-286 ° C (dec.) (lit.)
● Refractive Index: 1.7990 (kwv yees)
● Boiling Point: 288.5 ° C ntawm 760 mmHg
● PKA: 10.61 ± 0.50 (Predicted)
● Flash Point: 128.3 ° C
● PSA: 98.05000
● Ceev: 1.84 g / cm3
● LogP: 0.50900
● Cia Temp.: Desiccate ntawm +4 ° C
● Sensitive.: Lub teeb rhiab heev
● Solubility: DMSO (me ntsis), Methanol (me ntsis)
Purity/Quality
99% * cov ntaub ntawv los ntawm cov khoom siv raw
2,4-Diamino-6-hydroxypyrimidine * cov ntaub ntawv los ntawm cov chaw muag khoom reagent
Cov ntaub ntawv nyab xeeb
● Daim duab:
Xi
● Hazard Codes:Xi
● Nqe Lus: 36/37/38
● Cov Lus Qhia Txog Kev Nyab Xeeb: 22-24/25-36-26
MSDS Cov ntaub ntawv
Pab tau
● Nqe lus piav qhia: 2,4-Diamino-6-hydroxypyrimidine (DAHP) yog ib qho kev xaiv, tshwj xeeb inhibitor ntawm GTP cyclohydrolase I, tus nqi limiting kauj ruam rau de novo pterin synthesis.Hauv HUVEC hlwb, IC50 rau inhibition ntawm BH4 biosynthesis yog li 0.3 mM.DAHP tuaj yeem siv los thaiv tsis muaj ntau lawm hauv ntau hom cell.
● Siv: 2,4-Diamino-6-hydroxypyrimidine (DAHP) yog ib qho kev xaiv, tshwj xeeb inhibitor ntawm GTP cyclohydrolase I, tus nqi limiting kauj ruam rau de novo pterin synthesis.Hauv HUVEC hlwb, IC50 rau inhibition ntawm BH4 biosynthesis yog li 0.3 mM.DAHP tuaj yeem siv los thaiv tsis muaj kev tsim tawm hauv ntau hom xovtooj. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) yog ib qho khoom siv hauv cov organic synthesis.
2,4-Diamino-6-hydroxypyrimidine yog cov tshuaj sib xyaw nrog cov mis molecular C4H6N4O.Nws yog feem ntau siv los ua ib qho nruab nrab hauv kev sib txuas ntawm ntau lub tebchaw, suav nrog cov tshuaj siv tshuaj thiab cov tshuaj dyes.Cov tshuaj muaj ib lub nplhaib pyrimidine uas muaj ob pawg amino (NH2) thiab ib pawg hydroxyl (OH) txuas rau cov pa roj carbon sib txawv.Cov qauv no ua rau nws muaj ntau lub tsev thaiv rau cov synthesis ntawm ntau cov molecules.2,4-Diamino-6-hydroxypyrimidine tuaj yeem tau los ntawm ntau txoj kev hluavtaws, nrog rau cov tshuaj tiv thaiv ntawm cyanamide nrog urea.Nws muaj ntau daim ntawv thov nyob rau hauv kev lag luam kws, tshwj xeeb tshaj yog nyob rau hauv cov synthesis ntawm anticancer tshuaj thiab tshuaj tua kab mob.Zuag qhia tag nrho, 2,4-Diamino-6-hydroxypyrimidine yog ib qho tseem ceeb compound uas pom kev siv nyob rau hauv ntau yam tshuaj thiab tshuaj daim ntawv thov.
