Khoom
![3- [TIS- (hydroxymethyl) -Methylamino] -1-propanesulfonic acid; Cas.: 29915-38-6 Featured Duab](https://cdn.globalso.com/pengnuochemical/3-13-Dihydroxy-2-hydroxymethylpropan-2-ylazaniumylpropane-1-sulfonate-29915-38-6.png)
3- [TIS- (hydroxymethyl) -Methylamino] -1-propanesulfonic acid; Cas.: 29915-38-6
![3 - [1,3-Dihydroxy-2- (hydroxymethyl) propan-2-YL] Azaniumyl] Prozaniumther] Proxant-1-Sulfonate 29915-38-6](http://www.pengnuochemical.com/uploads/3-13-Dihydroxy-2-hydroxymethylpropan-2-ylazaniumylpropane-1-sulfonate-29915-38-6.png)
Txhais lus hais tias: 3- (TRIS (Hydroxymethyl) metyllamino) -1-propanesulfonic acid; taps cpd
Tshuaj Khoom Siv Ntawm Cov Taps
Winds Ntag / Xim: Dawb / Vinin Crystalline Hmoov
● Melting point: 230-235 ° C (Dec.)
● Cov ntsiab lus tsis zoo: 1.559
● PKA: 8.55; PKA (37 °): 8.1; PKA2 (25 °): 8.28
Flash taw tes: 110 ° C
● Psa:135.47000
Wensity: 1.483 G / cm3
● LogP: -0.95870
● Cia Champ. :Ttore ntawm RT.
● Solubility.:h2o: 1 m ntawm 20 ° C, ntshiab, tsis muaj kob
● Dej Solubility.:Soluble
● XlogP3: -5.4
It Hydrogen BRonor pub nyiaj: 5
● Hydrogen Brinter Txais Txais Suav: 7
Resot Rotatable Bond COUNTER: 8
● Muaj tseeb tiag tshua: 243.077765844
● Hnyav Hom Dav: 15
● Nyuaj: 247
Cov Ntaub Ntawv Safty
● POTOSSGRAM (S):
Xi
● Cov cai phom sij: xi
● Cov nqe lus: 36/37/38
● Cov nqe lus kev nyab xeeb: 22-24 / 25-36-26
Zoo siv
Tshuaj lom neeg:Lwm Yam Siv -> Kev Raug Mob Buffers
Canonical luag nyav:C (cnc (co) (co) CO) CS (= O) (= O) O
Siv:Zwitterionic zoo tus tsis
Cov lus qhia ntxaws ntxaws
Tus kais dej, tseem hu ua n-tris (hydroxymethyl) methyl-3-aminopropanesulfonic acid, yog lwm tus neeg sawv cev buffering nquag siv hauv biochemical thiab kev tshawb fawb txog roj ntsha. Ntawm no yog qee cov ntsiab lus tseem ceeb txog taps:
Cov Khoom Siv Buffing:Cov kais dej yog ib tus neeg sawv cev ua haujlwm zoo uas tuaj yeem tswj hwm cov hom ntawm 7.7-9.1. Nws PKA tus nqi yog 8.46, uas ua rau nws haum rau kev daws teeb meem tsis pub dhau ntawm cov phot no.
Stability:Cov kais dej yog paub rau nws qhov kev ruaj khov zoo tshaj li ntau yam ntawm cov kub, ua rau nws muaj txiaj ntsig hauv kev sim uas yuav tsum muaj pH tswj kom meej. Nws tsis tshua muaj kev cuam tshuam los ntawm qhov kub hloov pauv piv rau lwm cov neeg sawv cev ntawm cov neeg sawv cev thiab cov phosphate buffers.
Kev Siv Hluav Taws Xob:Cov kais dej yog feem ntau siv nyob rau hauv ntau cov roj ntsha thiab cov kev sim biochemical, xws li protein purification, enzyme cia, thiab DNA / RNA Kev rho tawm. Nws qhov kev ua tau zoo ua tau muaj peev xwm thiab kev ruaj khov ntawm Physiological Ph Phaj Ua rau nws siv tau hauv cov ntsiab lus no.
Cellure Culture:Cov kais dej tseem tuaj yeem ua raws li tus neeg sawv cev buffering hauv cell kev cai xov xwm. Nws lub peev xwm tsis muaj peev xwm pab nyob rau hauv kev tswj xyuas pH ib puag ncig rau kev loj hlob ntawm tes thiab txij nkawm.
Sib xyaw thiab ions:Zoo li EPPS, cov kais dej yog lub zwitterionic sib xyaw, txhais tau nws muaj cov nqi zoo thiab tsis zoo. Cov xeeb ceem no ua rau nws ua tau zoo rau kev ua kom muaj ob qho tib si acidic thiab cov kev daws teeb meem yooj yim. Cov kais dej yog sib xws nrog ntau cov roj ntsha lwg me me thiab muaj kev cuam tshuam tsawg tsawg nrog kev phiv tshuaj enzymatic.
Thaum siv cov kais dej, nws yog ib qho tseem ceeb kom ua raws li kev pom zoo thiab ph cov txheej txheem ntawm cov khw. Nco ntsoov xyaum ua kev nyab xeeb kom nyab xeeb thaum tuav ib qho tshuaj lom neeg lossis tus neeg sawv cev buffering.
