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Cov khoom

3-Morpholinopropanesulfonic acid

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  • Khoom npe:3-Morpholinopropanesulfonic acid
  • Synonyms:MOPS; MOPS, CONCENTRATE SOLUTION; MORPHOLINOPROPANE SULFONIC ACID; TIMTEC-BB SBB009133; 4-MORPHOLINE PROPANESULFONIC ACID; 4-(MORPHOLINOPROPANE SULFONIC ACID); 3-MORPHOLINOPROPANICAL ACID ID
  • CAS:1132-61-2
  • MF:C7H15NO4S
  • MW:209.26 Nws
  • EINECS:214-478-5 ib
  • Khoom Categories:Imidazoles; Buffer; Lwm yam Biochemicals; Organic acids; Biochemistry; Good's Buffers
  • Mol File:1132-61-2. mol
  • Product Detail

    Khoom cim npe

    asdasd 1

    Morpholinopropanesulfonic acid Chemical Properties

    Melting point 277-282 ° C
    ceev 1.3168 (kev kwv yees kwv yees)
    vapor siab 0Pa ntawm 25 ℃
    Refractive Index 1.6370 (kwv yees)
    Fp 116 ° C
    cia temp. chav kub
    solubility H2O: 1 M ntawm 20 ° C, ntshiab
    daim ntawv Hmoov / Khoom
    xim Dawb
    tsw Tsis hnov ​​tsw
    PH 2.5-4.0 (25 ℃, 1M hauv H2O)
    PH Range 6.5-7.9 Nws
    pka ua 7.2 (ntawm 25 ℃)
    Dej Solubility 1000 g / L (20 ºC)
    lw max λ: 260 nm Amax: 0.020
    λ: 280 nm Amax: 0.015
    Merck 14,6265 ib
    BRN 1106776 ib
    Kev ruaj ntseg: ruaj khov.Incompatible nrog cov hauv paus muaj zog, muaj zog oxidizing tus neeg sawv cev.
    InChIKey DVLFYONBTKHTER-UHFFFAOYSA-N
    LogP -2.94 ntawm 20 ℃
    CAS DataBase Reference 1132-61-2 (CAS DataBase Reference)
    EPA Tshuaj Registry System 4-Morpholinepropanesulfonic acid (1132-61-2)

    Cov ntaub ntawv kev nyab xeeb

    Hazard Codes Xi
    Risk Statements 36/37/38 ib
    Cov lus hais txog kev nyab xeeb 26-36 : kuv
    WGK Germany 1
    RTECS QE9104530
    TSCA Yog lawm
    HS Code 293499 0

    Morpholinopropanesulfonic acid Siv thiab Synthesis

    Kev piav qhia MOPS (3-morpholinopropanesulfonic acid) yog ib qho tsis qhia los ntawm Good et al.hauv xyoo 1960s.Nws yog ib qho qauv analog rau MES.Nws cov qauv tshuaj muaj ib lub nplhaib morpholine.HEPES yog ib qho zoo sib xws pH buffering compound uas muaj lub nplhaib piperazine.Nrog pKa ntawm 7.20, MOPS yog qhov tsis zoo rau ntau cov kab mob lom neeg nyob ze- nruab nrab pH.Nws yog siv los ua cov khoom siv hluavtaws hauv qab pH 7.5.
    daim ntawv thov MOPS feem ntau yog siv los ua tus neeg sawv cev buffering hauv biology thiab biochemistry.Nws tau raug kuaj thiab pom zoo rau polyacrylamide gel electrophoresis.Kev siv ntau dua 20 mM hauv kev ua haujlwm ntawm cov kabmob ntawm tes yog tsis pom zoo.MOPS cov kev daws teeb meem tsis zoo dhau los ua xim daj (daj) dhau sijhawm, tab sis tshaj tawm tias kev hloov xim me ntsis tsis cuam tshuam rau cov yam ntxwv buffering.
    Kev siv PH Quail, D. Marme, E. Schäfer, Particle-bound phytochrome los ntawm pob kws thiab taub dag, Nature New Biology, 1973, vol.245, pp. 189-191 : kuv
    Chemical Properties Dawb / ntshiab crystalline hmoov
    Siv 3-(N-Morpholino) propanesulfonic acid lossis MOPS vim nws qhov tsis zoo yog qhov nyiam thiab siv dav hauv ntau cov kev tshawb fawb biochemical.
    MOPS tau siv los ua:
    cell culture additive tivthaiv nyob rau hauv lentiviral particle zus tau tej cov.
    raws li tus neeg sawv cev buffering nyob rau hauv microbial loj hlob nruab nrab thiab nuclei extraction tsis.
    raws li ib feem ntawm Roswell Park Memorial Institute (RPMI) nruab nrab rau diluting fungal inoculum.
    raws li qhov tsis nyob hauv capillary-zone electrophoresis los kuaj kev ua haujlwm.
    rau dilution ntawm cov proteins los ntawm cov qauv algal.
    Siv MOPS ua raws li ntau lub hom phiaj buffering siv nyob rau hauv ntau yam kev tshawb fawb lom.
    Siv MOPS tau siv los ua:

    • cell culture additive tivthaiv nyob rau hauv lentiviral particle zus tau tej cov
    • raws li tus neeg sawv cev buffering nyob rau hauv microbial loj hlob nruab nrab thiab nuclei extraction tsis

     

    Txhais ChEBI: 3-(N-morpholino)propanesulfonic acid yog ib yam khoom zoo, pKa = 7.2 ntawm 20 ℃.Nws yog ib tug tswv cuab ntawm morpholines, MOPS thiab organosulfonic acid.Nws yog conjugate acid ntawm 3-(N-morpholino)propanesulfonate.Nws yog tautomer ntawm 3-(N-morpholiniumyl)propanesulfonate.
    Kev piav qhia dav dav 3-(N-Morpholino) propane sulfonic acid (MOPS) yog ib qho N-hloov cov amino sulfonic acid nrog lub nplhaib morpholinic.MOPS muaj peev xwm ntawm buffering nyob rau hauv pH ntau ntawm 6.5-7.9.MOPS tau siv dav hauv kev tshawb fawb txog roj ntsha thiab biochemical vim nws cov khoom tsis muaj zog.Nws tsis cuam tshuam nrog cov hlau ions hauv cov kev daws teeb meem thiab muaj qhov tseem ceeb ntawm cov hlau tsis ruaj khov tshwj xeeb nrog tooj liab (Cu), npib tsib xee (Ni), manganese (Mn), zinc (Zn), cobalt (Co) ions.MOPS tsis tswj cov pH ntawm cov kab lis kev cai ntawm cov tsiaj.MOPS ua haujlwm los tswj pH hauv denaturing gel electrophoresis ntawm RNA.MOPS tuaj yeem hloov kho lipid kev sib cuam tshuam thiab cuam tshuam cov thickness thiab thaiv cov khoom ntawm daim nyias nyias.MOPS cuam tshuam nrog bovine serum albumin thiab stabilizes cov protein.Hydrogen peroxide oxidizes MOPS maj mam mus rau N-oxide daim ntawv.
    Flammability thiab Explosibility Tsis cais

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