4-Hydroxy-D-(-)-2-phenylglycine

Lus piav qhia luv luv:

Khoom npe:4-Hydroxy-D-(-)-2-phenylglycine

Synonyms:4-HYDROXY-D-PHENYLGLYCINE;(R)-(-)-AMINO(4-HYDROXYPHENYL)ACETIC ACID;(R)-Amino-(4-HYDROXY-PHENYL)-aceTIC ACID;(r)-alpha-amino- 4-hydroxybenzeneacetic acid;(R)-ALPHA-AMINO-4-HYDROXYPHENYLACETIC ACID;(R)-4-HYDROXYPHENYLGLYCINE;(R)-(-)-2-(4-HYDROXYPHENYL)GLYCIN; -(4-HYDROXYPHENYL)GLYCINE

CAS:22818-40-2

MF:C8H9NO3

MW:167.16 Nws

EINECS:245-247-7 ib

Khoom Categories:Antidote / Tshuaj tua kab mob / tshuaj tua kab mob; Lwm yam Biochemicals; Amino ACIDS SERIES; Cephalosporins; Peptide Synthesis; Phenylglycine Derivatives; Pharmaceutical Intermediates; Unnatural Amino Acid Derivatives; Odevixibat

Mol File:22818-40-2. mol

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Product Detail

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Phenylglycine Chemical Properties

Melting point	240 ° C (txog) (lit.)
alpha	-156 º (c = 1, 1 N HCl)
Boiling point	295.73 ° C (kwv yees kwv yees)
ceev	1.396 ib
vapor siab	0Pa ntawm 25 ℃
Refractive Index	-158 ° C = 1, 1 mol / L HCl)
cia temp.	2-8 ° C
solubility	5 g/l
pka ua	2.15 ± 0.10 (Kev kwv yees)
daim ntawv	Ua kua
xim	Ntshiab xim tsis muaj xim rau daj
kev ua haujlwm kho qhov muag	[α]23/D 158 ± 3°, c = 1 in 1 M HCl
Dej Solubility	5 g / L (20 ºC)
BRN	2210998 ib
LogP	- 2.25
CAS DataBase Reference	22818-40-2 (CAS DataBase Reference)
EPA Tshuaj Registry System	Benzeneacetic acid, .alpha.-amino-4-hydroxy-, (.alpha.R)- (22818-40-2)

Cov ntaub ntawv kev nyab xeeb

Hazard Codes	Xi
Risk Statements	36/37/38 ib
Cov lus hais txog kev nyab xeeb	26-36-24/25 ib
WGK Germany	3
TSCA	Yog lawm
HS Code	29225 000 Nws

Phenylglycine Siv thiab Synthesis

Chemical Properties	hmoov av dawb
Siv	4-Hydroxy-D-(-)-2-phenylglycine yog ib qho khoom siv feem ntau siv rau kev npaj cov tshuaj tua kab mob β-lactam.
Siv	4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A (Amoxicillin EP Impurity A)) yog ib qho khoom siv feem ntau siv rau kev npaj hluavtaws ntawm β-lactam tshuaj tua kab mob.
Txhais	ChEBI: D-enantiomer ntawm 4-hydroxyphenylglycine.Ib qho non-proteinogenic amino acid pom hauv Herpetosiphon aurantiacus.
Flammability thiab Explosibility	Nonflammable
Txoj kev Purification	Crystallize nws los ntawm dej thiab qhuav nws hauv vacuo.[Beilstein 14 I 659.]