Cov khoom
4-Hydroxy-D-(-)-2-phenylglycine
Synonyms: (R,S)-3HPG; 4-hydroxyphenylglycine; 4-hydroxyphenylglycine hydrobromide, (+-)-isomer; 4-hydroxyphenylglycine hydrochloride, (R)-isomer; 4-hydroxyphenylglycine perchlorate, (+-)-isomer; -hydroxyphenylglycine, (+-)-isomer; 4-hydroxyphenylglycine, (R)-isomer; 4-hydroxyphenylglycine, (S)-isomer; 4-hydroxyphenylglycine, 2,4-dimethylbenzenesulfonate, (+-)-isomer; 4-hydroxyphenylglycine, , 2,4-dimethylbenzenesulfonate, (R)-isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (+-)-isomer; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (S)-isomer; -hydroxyphenylglycine, monosodium ntsev, (R)-isomer; Dp-hydroxyphenylglycine; L-4-hydroxyphenylglycine; oxfenicine; p-hydroxyphenylglycine; UK 25842; UK-25842
Chemical Property of D(-)-4-Hydroxyphenylglycine
● Cov tsos / Xim: tawm-dawb hmoov
● Vapor Pressure: 0.000272mmHg ntawm 25 ° C
● Melting Point: 240 ° C (dec.) (lit.)
● Refractive Index: -158 ° (C = 1, 1mol / L HCl)
● Boiling Point: 365.8 ° C ntawm 760 mmHg
● PKA: 2.15 ± 0.10 (Predicted)
● Flash Point: 175 ° C
● PSA: 83.55000
● Ceev: 1.396 g / cm3
● LogP: 1.17690
● Cia Kub: Khaws hauv qab +30 ° C.
● Solubility: 5g / l
● Dej Solubility: 5 g / L (20 ºC)
● XLogP3:-2.1
● Hydrogen Bond Donor Count: 3
● Hydrogen Bond Txais Tus Nqi: 4
● Rotatable Bond suav: 2
● Exact Mass: 167.058243149
● Heavy Atom suav: 12
● Kev nyuaj: 164
Purity/Quality
99% * cov ntaub ntawv los ntawm cov khoom siv raw
4-Hydroxy-D-(-)-2-phenylglycine * cov ntaub ntawv los ntawm cov chaw muag khoom reagent
Cov ntaub ntawv nyab xeeb
● Daim duab:
Xi
● Hazard Codes:Xi
● Nqe Lus: 36/37/38
● Cov Lus Qhia Txog Kev Nyab Xeeb: 26-36-24/25
MSDS Cov ntaub ntawv
Pab tau
● Canonical SMILES: C1=CC(=CC=C1C(C(=O)O)N)O
● Isomeric SMILES: C1=CC(=CC=C1[C@H](C(=O)O)N)O
● Siv: 4-Hydroxy-D-(-)-2-phenylglycine yog ib qho tshuaj siv los ua cov tshuaj tua kab mob β-lactam.4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A (Amoxicillin EP Impurity A)) yog ib qho khoom siv feem ntau siv rau kev npaj hluavtaws ntawm β-lactam tshuaj tua kab mob.
4-Hydroxy-D-phenylglycine, tseem hu ua 4-hydroxy-D-phenylglycine lossis 4-HDPG, yog cov tshuaj sib xyaw nrog cov mis molecular C8H9NO3.Nws yog ib qho amino acid derivative thiab belongs rau qeb ntawm phenylglycines.4-Hydroxy-D-phenylglycine feem ntau yog siv los ua ib lub tsev thaiv nyob rau hauv cov synthesis ntawm cov tshuaj tebchaw.Nws ua haujlwm raws li cov khoom siv raw hauv kev tsim cov tshuaj tua kab mob, xws li cefadroxil thiab cephradine.Cov tshuaj tua kab mob no muaj nyob rau hauv chav kawm cephalosporin thiab siv los kho cov kab mob kab mob.Ntxiv rau nws lub luag haujlwm ua tus thawj coj hauv kev siv tshuaj, 4-Hydroxy-D-phenylglycine kuj tau tshawb xyuas rau nws cov peev xwm kho mob.Kev tshawb fawb qhia tias nws yuav muaj cov tshuaj tua kab mob antioxidant thiab tiv thaiv kab mob, uas tuaj yeem ua rau nws muaj txiaj ntsig zoo hauv kev tsim cov tshuaj tshiab rau ntau yam kev kho mob.Zuag qhia tag nrho, 4-Hydroxy-D-phenylglycine yog cov tshuaj sib xyaw nrog cov kev siv tseem ceeb hauv kev tsim tshuaj thiab muaj peev xwm. siv kho mob.Nws lub luag haujlwm ua lub tsev thaiv hauv kev tsim cov tshuaj tua kab mob qhia txog nws qhov tseem ceeb hauv kev lag luam kws tshuaj.
