Khoom
4-Hydroxy-D - (-) - 2-phenylglycine; CAS MUAJ: 22818-40-2
Cov Lus Txhais: (R, S) -3HPG; 4-hydroxyphenycleglycine hydrochly, (r) -isomer; 4-hydroxyphenyfglycine perchlororate, (+ - omoxy; 4-hydroxyphenyfglycine, (+ - hydroxyphenyfglycine, (r) -isomer; 4-hydroxyphenycleglycine, 2,4-dimethylbenesulfonate, (+ - omoer; 4-hydroxyphenycleglycine, 2,4-didylbenesulfonate, (om omerinphenyfglycine, 4-methylbenesulfonate, (S) -isomer; 4-hydroxyphenyfglycine, Monosodium ntsev; oxfenium; p-hydroxyphenyfglycine; UK 25842; UK 25842
Cov Khoom Muaj Tshuaj Ntawm D (-) - 4-hydroxyphenylglycine
Winds Ntag / Xim: OFF-dawb hmoov
Pro vapor siab: 0.000272mmhg ntawm 25 ° C
● Melting point: 240 ° C (Dec.) (Lit.)
● Cov ntsiab lus tsis zoo: -158 ° (c = 1, 1mol / L HCl)
● Bowing taw tes: 365.8 ° C ntawm 760 MMHG
● PKA: 2.15 ± 0.10 (kwv yees)
Flash taw tes: 175 ° C
● Psa: 83.55000000
Ceev Ntiab: 1.396 G / CM3
● Cov cim: 1.17690
● Chaw Nres Temp.:Nore hauv qab + 30 ° C.
● Solubility.:5g/l
● Solubility DEJ.:5 G / L (20 ºC)
● XlogP3: -2.1
Itydrogen BRonor Pub pub Suav: 3
Hydrogen BRRong tau txais kev lees paub: 4
Resot Rotatable Bond COUNTER: 2
● Muaj tseeb pes tsawg kawg: 167.058243149
● Cov kab mob hnyav: 12
Comllexity: 164
Cov Ntaub Ntawv Safty
● POTOSSGRAM (S):
Xi
● Cov cai phom sij: xi
● Cov nqe lus: 36/37/38
● Cov nqe lus kev nyab xeeb: 26-36-24 / 25
Zoo siv
● Canonical smiles: c1 = CC = CC = C1C (CC (= O) O) O
Isomeric luag: C1 = CC = CC = C1 [CC = C1 [C @ H] (C (= O) O) O
● Siv cov: 4-hydroxy-D - (-) - 2-phenylglycine yog ib qho compound siv feem ntau rau cov khoom siv hluavtaws ntawm β-lactam tshuaj tua kab mob. 4-Hydroxy-D - (-) - 2-phenylglycine (Amfadroxil Ep Impurity A (Amfadroxil Ep (Amfadroxil A (Amfadroce Ep
Cov lus qhia ntxaws ntxaws
4-hydroxy-d-phenylglycine, tseem hu ua 4-hydroxy-d-phenylglycine lossis 4-HDPGLYCINE lossis 4-HDPGY lossis 4-HDPG, yog cov tshuaj molecular C8h9No3. Nws yog amino acid derivative thiab belongs rau qeb ntawm phenylglycines.c-hydroylgly-d-phenylglycine feem ntau yog siv los ua hluav taws xob ntawm cov tshuaj sib xyaw. Nws pabcuam ua cov khoom siv raw hauv kev tsim cov tshuaj tua kab mob, xws li Cefadroxil thiab Cephadine. Cov tshuaj tua kab mob no muaj rau cov kab mob cepharosporin thiab tau siv los kho cov kab mob no yog cov khoom siv ua ntej ntawm cov khoom siv hluav taws xob. Kev tshawb fawb qhia tias nws yuav muaj antioxidant thiab anti-incammogy-d-phenylgly-d-phenylglycine yog ib qho kev siv tshuaj rau cov ntaub ntawv tseem ceeb hauv cov ntaub ntawv tseem ceeb hauv cov ntaub ntawv tseem ceeb hauv kev siv hluav taws xob. Nws lub luag haujlwm yog lub tsev thaiv hauv kev tsim cov tshuaj tua kab mob tseem ceeb tshaj nws qhov tseem ceeb hauv kev lag luam kws tshuaj.
