Txhais lus hais tias: 6212-33-5; 2-amino-2- chlorophenyl) aceticly acid; dl-4-chlorophenyclycine; amino- (4-cenyyl) -acetic acid; 4-chlorophenylglycine; dl- (4-chlorophenyl) glycine; .alpha.-amino-4-chloro-; l-4-chloro-dl-phenylglycine; MFCD03839815; h -dl-phg (4-cl) -oh; rm2jw43tga; 2- (p-chlorophenyl) Glycine; DL-2- (4-chlorophenyl ); 4-chloro-dl-2-phenylglycine; DL-2- (P-Chlorophenyl) Glycine; amino (4-chlorophenyl) acetic acid #; BCP25773; BBL02263; BLBM50179705; AKOSTYRCATE ACC; SMKOS0869147; Amino-4-Chlorobenzetycete acid; 7l-304s; ab02094; ab1670; ab2870; Acid; sy017756; ser034115; FT034300200; FT-0625; FT-068024; >=98.0% (TLC);Q-102258;F2147-0645;Z317024646;(+/-)-4-CHLOROPHENYLGLYCINE 4-CHLOROPHENYL GLYCINE AMINO-(4-CHLORO-PHENYL)-ACETIC ACID (+/-)-ALPHA-AMINO-4-CHLOROPHENYLACETIC ACID
Cov tsos pom / xim: Dawb mus rau lub teeb Daj Crystal Hmoov
Vapor siab: 7.45e-05mmHG ntawm 25 ° C
● Melting point: 220-230 ° C
● Cov ntsiab lus tsis zoo: 1.603
● Boaring taw tes: 328.8 ° C ntawm 760 MMHG
● PKA: 1.81 ± 0.10 (kwv yees)
Flash taw tes: 152.7 ° C
● Psa:63.32000
Ceev ntom: 1.392 g / cm3
●: 2.12470
● Cia temp.heep hauv qhov chaw tsaus, Inert huab cua, chav sov
● Solubility.: :Moluble hauv 0.1Mol / L Naoh (yuav luag pob tshab).
● XlogP3: -1.1
Hydrogen BRonor Pub pub Suav: 2
Hydrogen BRRongle Txais Txais Suav: 3
Resot Rotatable Bond COUNTER: 2
● Muaj tseeb tiag tshua: 185.0243562
● Cov kab mob hnyav: 12
● Cov neeg nyuaj: 166
Canonical luag nyav:C1 = CC (= CC = C1C (C (= O) O) N) CL
Siv:Nws yog ib qho tseem ceeb raw thiab intermediation siv nyob rau hauv cov organic synthesis, tshuaj, agnchemicals thiab dyestuff.
2-amino-2- (4-chlorophenyl) acetic acid tseem muaj cov tshuaj, 4-chloro-alinha-aminobenenzety acid. Nws yog hmoov dawb huv nrog cov tshuaj molecular ntawm C8H8CLNo2 thiab qhov hnyav molecular hnyav ntawm 185.61 g / mol.
Nov yog qee cov ntsiab lus ntxiv txog 2-amino-2- (4-chlorophenyl) acetic acid:
Synthesis:Cov compound no tuaj yeem ua tau zoo los ntawm ntau txoj kev, nrog rau cov tshuaj tiv thaiv 4-chloroacetophenone nrog Sodium ntawm 4-chlorophenacyl bromide nrog sodium glycinate.
Lub cev thiab tshuaj lom neeg:
1.Melting taw tes: lub ntsiab lus melting ntawm 2-amino-2- (4-chlorophenyl) acetic acid feem ntau yog nyob ib puag ncig 135-140 ° C.
2.
3.Ph: Hauv cov kuab tshuaj aqueous, qhov sib xyaw no tsis muaj zog acidic nrog pH nyob ib ncig ntawm 5-6.
Cov Khoom Kho Mob Biological:
1.Txoj kev ua si: txawm hais tias muaj cov ntaub ntawv tsawg ntawm 2-amino-2- chlorophenyl) acetic acid, qee cov kev tshawb fawb qhia tau tias nws yuav muaj tej zaum los tiv thaiv thiab ua piv txwv.
2.Metabolism: txoj hmoo metabolic ntawm qhov sib txuas no hauv tib neeg tsis yog cov ntaub ntawv zoo. Txawm li cas los xij, nws yuav tsum tau yauv yauv mus sab enzymatic tawg thiab tshem tawm ntawm lub cev.
Kev Saib Xyuas Kev Nyab Xeeb:
1.While 2-amino-2- (4-chlorophenyl) acetic acid feem ntau, nws raug nquahu kom muaj kev ceev faj thiab ua raws cov kev nyab xeeb kev nyab xeeb thaum tuav lossis ua haujlwm nrog cov compound no.
2.Nws tseem ceeb rau cov khoom siv tiv thaiv, xws li hnab looj tes thiab goggles, thiab ua kom muaj kev ua haujlwm kom zoo thaum ua haujlwm nrog cov tshuaj no.
3.Viam qhia txog cov ntawv txheeb kev nyab xeeb (SDS) thiab sab laj kev nyab xeeb kev nyab xeeb thiab cov cai tswj hwm thaum tuav thiab siv cov compound no.
Nco ntsoov, cov ntaub ntawv tau muab ntawm no yog ib qho kev qhia dav dav thiab yuav tsum tsis txhob suav hais tias yog qhov tseeb. Txog cov ntawv thov tshwj xeeb lossis lub hom phiaj tshwj xeeb, nws ib txwm pom zoo los sab laj cov ntaub ntawv tshwj xeeb lossis cov ntaub ntawv uas tau ntseeg siab rau cov ncauj lus kom ntxaws.
2-amino-2- (4-chlorophenyl) acetic-alma-alinha-aminobenenzety acid, muaj cov ntawv thov muaj peev xwm hauv ntau thaj teb. Nov yog qee cov ntawv thov tau:
Kws Kev Lag Luam:
1.Cov cuab yeej siv tshuaj ua yeeb yam: Nws tuaj yeem siv ua lub tsev thaiv lossis nruab nrab hauv kev sib txuas ntawm cov tshuaj sib xyaw xws li cov tshuaj tiv thaiv, lossis cov kab mob tiv thaiv kab mob.
2.Prodrug Kev Loj Hlob: 2-amino-2- chlorophenyl) acetic acid yuav siv los tsim cov tshuaj produgs, uas tsis muaj zog los hloov dua siab tshiab hauv lub cev. Qhov no tuaj yeem pab txhim kho kev noj tshuaj ua tau zoo, bioavailability, lossis txo cov kev mob tshwm sim.
Tshuaj Kev Tshawb Fawb:
1.Organic synthesis: Cov compound tuaj yeem siv rau hauv chav kuaj rau cov tshuaj squthic synthesis cov tshuaj tiv thaiv, tshwj xeeb hauv synthesis ntawm cov orge compounds.
2.Ligand Synthesis: Nws yuav siv rau kev npaj ntawm Ligands rau kev ua kev sib koom tes rau kev sib koom tes rau kev siv tshuaj lom ntau.
Kev Lag Luam Kev Ua Liaj Ua Teb:
1.Tshuaj tua kab kev loj hlob: 2-amino-2- (4-chlorophenyl) acetic acid tuaj yeem siv tau los ua cov tshuaj tua kab lossis cov tshuaj tua kab mob uas muaj kev cuam tshuam zoo dua lossis txo cov kev cuam tshuam ib puag ncig.
Tshawb nrhiav thiab kev txhim kho:
1.Tshuaj Kev Tshawb Fawb: Cov ntais ntawv no yuav raug siv los ua tus qauv lossis siv txuas ntxiv rau cov hom phiaj ntsuas thiab txoj kev txhim kho hauv cov chaw tshawb fawb.
2.Kev tshawb fawb txog roj ntsha: siv tau rau hauv kev tshawb fawb tshawb xyuas lub luag haujlwm ntawm cov khoom siv ntawm cov neeg siv nyiaj txiag thiab lawv cov kev ua haujlwm hauv ntau lub cev lossis cov kab mob biochemical.
Thov nco ntsoov tias cov ntawv thov tshwj xeeb thiab siv 2-amino-2- (4-chlorophenyl) acetic acid yuav yog nyob ntawm kev tshawb fawb thiab kev loj hlob ntxiv. Cov ntawv nyeem sciatical, kev tswj hwm cov kev cai, thiab cov kws tshaj lij ua ntej siv lossis xaiv nws daim teb.