Khoom
N, n'-diisoprcarbodiimide; Cas.: 693-13-0
Txhais lus hais tias: 1,3-diisoprofcarbodiimide
Cov cuab yeej tshuaj lom neeg ntawm n, n'-diisoproylbodiimide
Winds Ntag / Xim: tsis muaj xim rau cov kua daj daj ntseg
Pro Vapor Siab: 34.9HPA ntawm 55.46 ℃
● Melting point: 210-212 ° C (Dec)
● Cov ntsiab lus tsis zoo: N20 / d 1.433 (lit.)
● Boaring taw tes: 146.5 ° C ntawm 760 MMHG
Flash taw tes: 33.9 ° C
● Psa:24.72000
Wensity: 0.83 G / cm3
● LOGP: 1.97710
● Cov temp.:2-882882
● Rhiab .:Moisture rhiab
● Solubility.: Athylene chloride, acetoniturile, Dioxane
● XlogP3: 2.6
It Hydrogen BRonor pub nyiaj: 0
● Hydrogen BR lees txais cov neeg lees paub: 2
Resot Rotatable Bond COUNTER: 2
● KEEB MEEM KEEB: 126.115698455
● Cov lej hnyav: 9
Inclexity: 101
Cov Ntaub Ntawv Safty
● POTOSSGRAM (T +,
T,
F
Cov kab mob nyuaj: T +, T, F, XN
● Cov nqe lus: 10-26-36 / 37 / 38-41-42 / 43-37 / 38
● Cov nqe lus kev nyab xeeb: 26-36 / 37 / 39-45-38-28A-16-22
Zoo siv
Tshuaj lom neeg:Nitrogen compound-> Lwm cov teb chaws nitrogen
Canonical luag nyav:Cc (c) n = NC (c) c
Tsis ntev los no EU kho mob sim:Ntev los ntawm Aldara? 5% cream thiab
Cov lus piav qhia piav qhia (dic) yog cov kua ntshiab uas tuaj yeem yooj yim tshaj tawm los ntawm ntim. Nws maj mam rov qab los ntawm noo noo los ntawm huab cua, yog li rau lub sij hawm ntev cia lub raj mis yuav tsum yaug nrog huab cua qhuav lossis hauv cov roj cua thiab khi kom nruj. Nws yog siv nyob rau hauv peptide chemistry raws li coupling reagent. Nws yog cov tshuaj lom heev thiab tshwm sim hu rau dermatitis hauv tus kws ua haujlwm hauv kev kuaj ua haujlwm.
Siv:Cov khoom no feem ntau yog siv nyob rau hauv amikacin, glutathione dehydrants, nrog rau hauv synthesis ntawm acid anhydride, aldehyde, Ketone, Isocyanate; Thaum nws tau siv los ua cov neeg sawv cev ua kom lub cev qhuav dej, nws cuam tshuam rau Dicyclohexylrea los ntawm lub sijhawm luv luv raws li qhov kub. Cov khoom no tseem tuaj yeem siv hauv synthesis ntawm peptide thiab nucleic acid. Nws yog ib qho yooj yim siv cov khoom no kom hnov cov compound ntawm cov carboxy dawb thiab amino-pawg ua peptide. Cov khoom no tau siv dav hauv kev kho mob, kev noj qab haus huv, ua-tu thiab khoom siv tshuaj lom neeg, thiab lwm yam hluavtaws teb. N, n'-diisoprcarbodiimide yog siv los ua cov reagent hauv cov organic organic. Nws pabcuam ua tshuaj lom neeg nrab thiab raws li lub stabilizer rau sarin (tshuaj lom neeg). Nws tseem siv nyob rau hauv synthesis ntawm peptide thiab nucleic acid. Ntxiv mus, nws yog siv los ua antineopastic thiab koom nrog kev kho mob ntawm malignant melamomat thiab sarcomas. Ntxiv rau qhov no, nws yog siv nyob rau hauv synthesis ntawm acid anhydride, aldehyde, Ketone thiab Isocyanate.
Cov lus qhia ntxaws ntxaws
N, n'-diisoprcarbodiimide, feem ntau tau luv luv li dic, yog cov tshuaj sib xyaw nrog cov mis molecular c7h14n2. Nws yog cov kua tsis muaj kob uas yog soluble nyob rau hauv cov organic cov kuab tshuaj zoo li cov neeg muaj kev nyab xeeb thiab dej cawv. DIC tau dav siv raws li cov tshuaj synthic synthesis reagent thiab plays lub luag haujlwm tseem ceeb hauv ntau yam tshuaj lom neeg.
Dic yog feem ntau siv los ua cov lej sib txuas hauv peptide synthesis, uas yog tus txheej txheem ntawm koom nrog amino acids ua ke los ua peptides lossis cov protein. Nws ua raws li cov condensing reagent, pab txhawb kev sib txuas ntawm cov amino acids los ntawm kev ua kom muaj kev tsim cov khoom tsis muaj peev xwm hu ua ib tus neeg ua haujlwm qub. Qhov nruab nrab no reacts nrog amino pawg ua ntej tab tom tab tom ua kom rov qab thiab tshem tawm cov nyiaj peptide.
DIC kuj tau ua haujlwm rau lwm yam kev tawm tsam tshaj li peptide synthesis, xws li cov kev siv Etrerification, thiab cov neeg siv, thiab Urethanes synthesis. Nws ua raws li tus neeg sawv cev ntawm lub cev qhuav dej hauv cov kev tiv thaiv no, kom tshem tawm cov kev tshem tawm dej lwg me me, yog li tsav cov kev xav tau.
Vim nws cov kev cuam tshuam thiab muaj ntxhiab tsw zoo, dic yuav tsum daws nrog kev ceev faj. Nws yog feem ntau siv nyob rau hauv ib qho zoo-ventilated hood thiab hnab looj tes yuav tsum tau hnav kom tiv thaiv kev sib cuag ntawm daim tawv nqaij. Ib qho ntxiv, raws li muaj tshuaj lom neeg, nws yog ib qho tseem ceeb kom ua tau cov txheej txheem kev nyab xeeb thiab sab laj cov ntaub ntawv kev nyab xeeb cov ntaub ntawv (MSDS) rau cov ncauj lus kom ntxaws.
Hauv cov ntsiab lus, n, n'-n'-n'-diisoprcarbodiimide yog ib qho hluavtaws ntau ntxiv, suav nrog peptide synthesis, xws li peptide synthesis, xws li cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, suav nrog peptide synthesis, xws li cov khoom siv peptide, xws li cov khoom siv peptide, thiab cov khoom siv rau hauv lub zog. Nws lub luag haujlwm ua cov neeg sawv cev thiab cov neeg sawv cev ua kom lub cev tsis muaj txiaj ntsig ua rau nws muaj txiaj ntsig zoo nyob hauv thaj teb cov agicic chemistry.
Daim ntawv thov
N, n'-diisoprcarbodiimide (dic) muaj ntau daim ntawv thov tseem ceeb hauv synthesis thiab kws tshawb fawb. Nov yog qee qhov kev siv dic:
Peptide synthesis:DIC feem ntau siv los ua coupling tus neeg sawv cev hauv cov khoom-theem peptide synthesis los ua peptide bonds ntawm amino acids. Nws ua kom cov pab pawg thauj khoom ntawm cov pab pawg muaj kev tiv thaiv cov amino acids, tso cai tawm tsam nrog cov pab pawg AMino, ua rau muaj kev tsim cov peptide.
Kev noj mov thiab cov khoom siv Esterification:Dic tau ua haujlwm ua cov neeg sawv cev qhuav dej los txhawb lub hws ntawm cov roj carboxylic nrog cov amines lossis dej cawv, feem ntau. Nws tau yooj yim tsim ntawm cov chaw nyob thiab esters los ntawm kev tshem dej los ntawm cov tshuaj tiv thaiv kab mob.
Urethane synthesis:DIC tuaj yeem siv los ua cov neeg sawv cev sib txuas hauv cov hluavtaws ntawm kev ua kom sib luag. Nws ua rau cov tshuaj tiv thaiv ntawm isocyanates thiab dej cawv los ua urethanes.
Carboodiimide-Mediar tseem ceeb:DIC feem ntau siv los ua cov repling reagent hauv ntau cov organic, xws li cov khoom siv hluav taws xob ntawm kev tawm suab, thiab lwm yam kev ua haujlwm lom zem. Nws txhawb nqa txuas ntawm carboxylic acids, acid chlorides, lossis acyl azides nrog amines, hydroxines, thiab lwm yam nucleophiles, thiab lwm yam nucleophiles, thiab lwm yam nucleophiles.
Oxidative Transformations:DIC tuaj yeem siv hauv oxidative cov tshuaj tiv thaiv, xws li oxidative cleavage ntawm Olefins thiab oxidation ntawm sulfoxides lossis sulfones.
Nws yog ib qho tseem ceeb kom nco ntsoov tias dic yog huab cua- thiab noo noo-nkag siab, yog li nws yuav tsum tau daws hauv qhov chaw muaj cua zoo lossis hauv qab cov khoom hauv inert. Tsis tas li ntawd, kev ceev faj kev nyab xeeb, xws li hnab looj tes thiab goggles, yuav tsum tau ua thaum ua haujlwm nrog dic vim nws qhov kev phom sij.
