Cov khoom
Phenylurea
Phenylurea Chemical Properties
| Melting point | 145-147 ° C (lit.) |
| Boiling point | 238 ° C |
| ceev | 1,302 g / cm²3 |
| vapor ceev | > 1 (vs huab cua) |
| Refractive Index | 1.5769 (kwv yees) |
| Fp | 238 ° C |
| cia temp. | Khaws nyob rau hauv qhov chaw tsaus, kaw hauv qhuav, Chav Kub |
| solubility | H2O: 10 mg / ml, ntshiab |
| pka ua | 13.37 ± 0.50 (Kev kwv yees) |
| daim ntawv | Hmoov, Crystals thiab / lossis Chunks |
| xim | Dawb rau lub teeb daj |
| Dej Solubility | Soluble hauv dej. |
| Merck | 14, 7319 ib |
| BRN | 19346 15 |
| Kev ruaj ntseg: | ruaj khov.Incompatible nrog muaj zog oxidizing neeg sawv cev. |
| InChIKey | LUBJCRLGQSPQNN-UHFFFAOYSA-N |
| CAS DataBase Reference | 64-10-8 (CAS DataBase Reference) |
| EPA Tshuaj Registry System | Urea, phenyl- (64-10-8) |
Phenylurea Product Description
6-Amino-1,3-dimethyluracil yog cov tshuaj sib xyaw nrog cov mis mos molecular C6H9N3O.Nws yog ib qho organic compound teej tug mus rau tsev neeg uracil.Cov compound muaj ib lub nplhaib uracil nrog ib pawg amino (NH2) txuas rau 6-txoj hauj lwm thiab ob pawg methyl (CH3) txuas rau 1- thiab 3-txoj hauj lwm.Cov qauv tshuaj muaj peev xwm qhia tau tias: txaus ||CH3--C--C--C--N--C--CH3 || ammonia 6-Amino-1,3-dimethyluracil yog ib qho nruab nrab hauv kev sib txuas ntawm ntau yam tshuaj sib txuas.Dav siv nyob rau hauv zus tau tej cov tshuaj antiviral thiab antitumor tshuaj.Nws yog cov khoom pib rau kev sib txuas ntawm nucleoside analogs rau kev kho mob ntawm tus kab mob thiab mob qog noj ntshav.
Tsis tas li ntawd, 6-amino-1,3-dimethyluracil kuj tseem siv rau hauv cov tshuaj pleev ib ce.Nws tuaj yeem siv los ua cov khoom siv hauv kev zoo nkauj thiab kev tu tus kheej xws li cov tshuaj pleev ib ce thiab tshuaj pleev ib ce.Nws cov khoom ua rau nws tsim nyog siv los ua cov tawv nqaij txias thiab moisturizer.Kev ceev faj txog kev nyab xeeb tsim nyog raug pom zoo thaum tuav 6-amino-1,3-dimethyluracil.Khaws rau hauv qhov chaw txias, qhuav kom deb ntawm hluav taws lossis cua sov.Tsis tas li ntawd, nws raug nquahu kom hnav cov khoom tiv thaiv tus kheej xws li hnab looj tes thiab tsom iav kom tiv thaiv kev sib cuag ncaj qha nrog cov khoom sib xyaw.
Hauv kev xaus, 6-amino-1,3-dimethyluracil yog ib qho organic compound siv los ua ib qho nruab nrab hauv kev sib txuas ntawm cov tshuaj, tshwj xeeb tshaj yog cov tshuaj tua kab mob thiab tshuaj tua kab mob.Nws kuj yog siv rau hauv tshuaj pleev ib ce rau nws cov tawv nqaij txias zog.Kev ceev faj txog kev nyab xeeb yuav tsum tau ua raws li thaum tuav cov khoom sib xyaw no.
Cov ntaub ntawv kev nyab xeeb
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Cov lus hais txog kev nyab xeeb | 22-36/37-24/25 ib |
| WGK Germany | 3 |
| RTECS | YU0650000 |
| TSCA | Yog lawm |
| HS Code | 29242100 ib |
| Toxicity | LD50 qhov ncauj hauv nas: 2gm / kg |
Phenylurea Kev Siv Thiab Synthesis
| Chemical Properties | Cov xim tsis muaj koob zoo li cov muaju lossis cov hmoov dawb dawb.Melting point 147 ° C (decomposition), soluble hauv dej kub, cawv kub, ether, ethyl acetate thiab acetic acid. |
| Siv | Phenylureas feem ntau siv cov av siv tshuaj tua kab mob rau kev tswj cov nyom thiab cov noob me me broadleaf weeds. |
| Siv | Phenyl urea yog siv rau hauv cov organic synthesis.Nws ua haujlwm zoo li ligand rau palladium-catalyzed Heck thiab Suzuki cov tshuaj tiv thaiv ntawm aryl bromides thiab iodides. |
| Kev npaj | Phenylurea yog synthesized los ntawm cov tshuaj tiv thaiv ntawm aniline thiab urea.Muab urea, hydrochloric acid thiab aniline rau hauv cov tshuaj tiv thaiv lub lauj kaub, tshav kub thiab do, reflux ntawm 100-104 ° C rau 1 teev, ntxiv dej thiab do, txias, lim, ntxuav lub lim ncuav mog qab zib nrog dej, thiab qhuav kom tau cov khoom tiav. ntawm phenylurea. |
| Daim ntawv thov | Phenyl urea tshuaj tua kab, kua, tshuaj lom tshwm sim raws li cov kua yaj los yog raug tshem tawm hauv cov khoom ua kua.Muaj ib qho ntawm ntau yam sib txuas (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) tau muab los ntawm urea.Carrier yog dej emulsifiable.Toxic los ntawm kev nqus, nqus ntawm daim tawv nqaij, los yog noj. |
| Kev piav qhia dav dav | Ib qho khoom los yog kua absorbed rau ntawm tus nqa khoom qhuav.Cov hmoov nplej ntub dej.Muaj ib qho ntawm ntau yam khoom lag luam (Diuron, Fenuron, Linuron, Monuron, Neburon, Siduron) tsim los ntawm urea.Toxic los ntawm kev nqus, nqus ntawm daim tawv nqaij, los yog noj.Tau txais lub npe ntawm cov tshuaj tua kab tshwj xeeb los ntawm cov ntawv xa khoom thiab hu rau CHEMTREC, 800-424-9300 rau cov lus teb. |
| Reactivity Profile | Organic amides / imides teb nrog azo thiab diazo tebchaw los tsim cov pa phem.Flammable gases yog tsim los ntawm cov tshuaj tiv thaiv ntawm cov organic amides / imides nrog cov muaj zog txo cov neeg ua haujlwm.Amides yog lub hauv paus tsis muaj zog heev (tsis muaj zog dua li dej).Imides tsis tshua muaj txiaj ntsig thiab qhov tseeb tshwm sim nrog cov hauv paus muaj zog los tsim cov ntsev.Ntawd yog, lawv tuaj yeem ua raws li cov kua qaub.Kev sib xyaw amides nrog cov dej ua kom lub cev qhuav dej xws li P2O5 lossis SOCl2 tsim cov nitrile sib xws.Lub combustion ntawm cov tebchaw no generates sib xyaw oxides ntawm nitrogen (NOx).Muaj ib qho ntawm ntau yam sib txuas (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) tau muab los ntawm urea. |
| Health Hazard | Cov tshuaj lom heev, yuav ua rau tuag taus yog tias nqus tau, nqos lossis nqus los ntawm daim tawv nqaij.Tsis txhob sib cuag ntawm daim tawv nqaij.Cov teebmeem ntawm kev sib cuag lossis nqus pa tuaj yeem ncua sijhawm.Hluav taws yuav ua rau khaus, corrosive thiab/los yog cov pa phem.Cov dej ntws los ntawm kev tswj hluav taws los yog cov dej dilution tuaj yeem ua rau corrosive thiab/los yog tshuaj lom thiab ua rau muaj kuab paug. |
| Hluav Taws Xob | Tsis-combustible, tshuaj nws tus kheej tsis hlawv tab sis yuav decompose raws li cua sov los tsim corrosive thiab/los yog tshuaj lom pa taws.Cov thawv ntim khoom tuaj yeem tawg thaum cua sov.Kev khiav dej num tuaj yeem ua rau cov dej tsis zoo. |
| Txoj kev Purification | Crystallize urea los ntawm boiling dej (10mL / g) los yog amyl cawv (m 149o).Qhuav nws nyob rau hauv ib lub qhov cub ntawm 100o.Lub 1: 1 resorcinol complex muaj m 115o (los ntawm EtOAc / * C6H6).[Beilstein 12 H 346, 12 II 204, 12 III 760, 12 IV 734.] |
