Khoom
Pyrimidine-2,4 (1h, 3h) -Dione; Case No.: 66-22-8
Txhais lus hais tias: Uracil
Cov Khoom Muaj Tshuaj Ntawm Pyrimidine-2,4 (1H, 3H) -Dione
Winds Ntag khaub Race / Xim: Cov hmoov dawb
Pro vapor siab: 2.27E-08mmHG ntawm 25 ° C
● Melting point:> 300 ° C (Lit.)
● Cov ntsiab lus tsis zoo: 1.501
● Boaring taw tes: 440.5 ° C ntawm 760 MMHG
● PKA: 9.45 (ntawm 25 ℃)
Flash taw tes: 220.2oc
● Psa:65.72000
Wensity: 1.322 G / cm3
● LogP: -0.93680
● Temp. ::+15C rau + 30c
● Solubility.:Aqueour acid (me ntsis), dmo (me ntsis, rhuab, sonicated), me ntsis,
● Dej solubility.: ansoluble hauv dej kub
● XlogP3: -1.1
Hydrogen BRonor Pub pub Suav: 2
● Hydrogen BR lees txais cov neeg lees paub: 2
Resetable Kev Muab Kev Rotatable Caud suav (0
● Muaj tseeb pes tsawg tus: 112.02727277375
● Cov lej hnyav: 8
Stratexity: 161
Cov Ntaub Ntawv Safty
● POTOSSGRAM (S):
Xi
● Cov cai phom sij: xi
Proferements Kev Nyab Xeeb Kev Nyab Xeeb: 22-24 / 25
Zoo siv
Tshuaj lom neeg:Cov neeg sawv cev roj ntsha -> nucleic acids thiab derivatives
Canonical luag nyav:C1 = CNC (= O) NC1 = O
Tsis ntev los no ClinialTs:Kev kawm txog 0.1% uracil kua qaub cream (UTC) rau kev tiv thaiv tes ntawm tes Syndrome
Tsis ntev los no EU kho mob sim:ONDERZOEK NAARACKETHE DE FORRICACKNETIE VAN UTACIL NA OTALE TO THEDIENING BOOV PATI?
Tsis ntev los no Niph kev sim siab: ib ntu II kev sim ntawm uracil ointment rau kev tiv thaiv ntawm capecitabine force syndrome (HFS) :.
Siv:Rau kev tshawb fawb biochemical, tshuaj squthesis; Raug siv los ua cov tshuaj nruab nrab, kuj siv hauv cov khoom siv hluav taws xob hauv nruab nrog cev ntawm rna nucleosides. Antelopastic hauv kev tshawb fawb biochemical. Uracil (Lamivudine EC Ipurity F) yog nitrogenous puag ntawm rna nucleosides.
Nqe lus piav qhia:Uracil yog pyrimidine puag thiab muaj lub hauv paus tseem ceeb ntawm RNA uas nws khi rau Adenine ntawm Hydrogen Bonds. Nws tau hloov mus rau hauv lub nucleoside uridine los ntawm kev sib ntxiv ntawm ib qho ntxiv ntawm ib qho kev sib ntxiv ntawm ib qho kev sib ntxiv, tom qab ntawd rau lub nucleotide uridhate los ntawm kev ntxiv ntawm cov tshuaj phosphothate.
Cov lus qhia ntxaws ntxaws
Uracil yog cov organic compound uas yog tsev neeg ntawm pyrimidine derivatives. Nws yog heterocyclic aromatic molecule muaj ib lub nplhaib pyrimidine nrog ob qho sib ze nitrogen atoms. Uracil muaj cov tshuaj noj tshuaj c4h4n2o2 thiab qhov hnyav molecular ntawm 112.09 G / Mol.
Uracil yog ib qho ntawm plaub nucleobases pom hauv cov khoom siv caj ces ntawm RNA (Ribonucleic acid). Nws plays lub luag haujlwm tseem ceeb hauv cov protein synthesis thiab cov noob. Hauv RNA, Uracil cov khub nrog Adenine ntawm hydrogen tsev, sib sau ob hydrogen bairs, thiab qhov no lub zog ua khub pab txhawm rau txheeb cov ntaub ntawv keeb kwm.
Uracil tseem tuaj yeem nrhiav tau hauv qee qhov tseem ceeb ntawm cov roj ntsha molecules. Piv txwv li, nws yog ib qho tseem ceeb ntawm lub zog-nqa molecule hu ua ATP (Adenosine Triphosphate). Uracil derivatives, xws li 5-fluorouracil, tau siv ua anticancer cov tshuaj tiv thaiv vim lawv lub peev xwm cuam tshuam nrog DNA replication thiab cell.
Ntxiv nrog rau nws txoj kev cuam tshuam, uracil muaj ntau yam tshuaj lom thiab kev siv khoom lag luam. Nws yog siv los ua cov khoom pib rau cov khoom siv hluav taws xob, agnchemicals, thiab dyes. Uracil derivatives tseem ua haujlwm hauv kev tsim cov tshuaj tua kab thiab cov fungicides. Tsis tas li ntawd, Urmil tuaj yeem siv los ua tus cim hauv kev tshawb xyuas anchistrical thiab raws li cov cuab yeej tshawb fawb biology biology biology.
Uracil yog cov khoom dawb khov kho cov khoom siv uas yog sparingly soluble hauv dej. Nws yog ruaj khov nyob rau hauv ib txwm muaj mob tab sis tuaj yeem yauv tsis txaus ntseeg, xws li oxidation thiab hloov cov cai, nyob rau hauv cov xwm txheej tshwj xeeb. Cov compound muaj lub ntsiab lus melting ntawm 335-338°C thiab ib qho npau npau ntawm 351-357°C.
Zuag qhia tag nrho, Uracil yog ib qho tseem ceeb hauv cov txheej txheem biological ntawm RNA thiab muaj cov ntawv thov tseem ceeb hauv kev lag luam roj ntsha thiab tshuaj lom neeg.
Daim ntawv thov
Uracil muaj ob peb daim ntawv thov hauv ntau thaj teb, suav nrog:
Kws Kev Lag Luam:Uracil thiab nws cov derivatives tau siv los tsim cov tshuaj rau ntau lub hom phiaj. Piv txwv li, 5-fluorouracil yog cov tshuaj kho tshuaj uas ib txwm siv los kho qee yam mob cancer. Uracil-raws cov tshuaj tua kab mob antiviral, xws li idoxuridine thiab trifluridine, tau siv los kho cov kab mob viral qhov muag.
Ua Liaj Ua Teb:Uracil derivatives yog siv hauv kev tsim cov tshuaj herbicides thiab fungicides. Cov tebchaw no pab tswj kev loj hlob ntawm cov nroj thiab tiv thaiv cov qoob loo los ntawm cov kab mob fungal.
Kev tshawb xyuas Anyistry:Uracil feem ntau yog siv los ua cov cim chromatographic lossis cov qauv sab hauv hauv kev ntsuas tshuaj chemicalsical. Nws tuaj yeem siv los ua cov ntaub ntawv sib txuas los txiav txim siab txog lub sijhawm khaws cia thiab kom muaj nuj nqis rau lwm cov tebchaw.
Kev Tshawb Fawb Molecular Biology:Uracil yog siv hauv ntau cov txheej txheem molecular biology, xws li polymerase cov tshuaj tiv thaiv (PCR), DNA cov kab ke, thiab xa cov ntawv tshaj tawm. Nws ua haujlwm ua tus qauv rau DNA synthesis los yog raws li ib feem rau kev tsim cov kev hloov pauv tshwj xeeb hauv DNA ua ntu zus.
Kev Lag Luam Khoom Noj:Uracil yog qee zaum tau siv los ua cov tsw ntxiv hauv kev lag luam khoom noj khoom haus, tshwj xeeb hauv kev tsim cov zaub mov ua thiab dej haus.
Cov tshuaj pleev ib ce:Uracil derivatives tau siv hauv cov khoom siv tshuaj pleev ib ce rau lawv cov moisturizing thiab tawv nqaij-seeb cov khoom. Lawv yuav pab txhim kho cov dej ua kom tawv nqaij thiab tiv thaiv kev ntxhov siab ib puag ncig.
Tshawb nrhiav thiab kev txhim kho:Uracil kuj tseem ua haujlwm nyob rau hauv cov kev tshawb fawb thiab kev tshawb fawb ntawm cov neeg muag khoom lossis nruab nrab rau kev sib txuas nrog lwm cov tebchaw nrog kev ua haujlwm roj ntsha lossis rau kev kawm nucleic acid metabolism.
Uracil cov kev siv ntawm ntau cov kev siv tau pom tias nws tseem ceeb hauv cov liaj teb xws li cov tshuaj ua liaj ua teb, kev ua liaj ua teb, cov tshuaj khib nyiab, thiab biotechnology, thiab biotechnology, thiab biotechnology, thiab biotechnology, thiab biotechnology. Cov kws tshawb nrhiav txuas ntxiv tshawb nrhiav txoj hauv kev tshiab rau nws cov khoom rau kev nce qib ntxiv hauv cov chaw no.
