Cov khoom
Uracil Pyrimidine-2,4 (1H, 3H)-dione
Synonyms: Uracil
Chemical Property ntawm Uracil
● tsos / Xim: hmoov dawb
● Vapor Pressure: 2.27E-08mmHg ntawm 25 ° C
● Melting Point:> 300 ° C (lit.)
● Refractive Index: 1.501
● Boiling Point: 440.5 ° C ntawm 760 mmHg
● PKA: 9.45 (ntawm 25 ℃)
● Flash Point: 220.2oC
● PSA: 65.72000
● Ceev: 1.322 g / cm3
● LogP:-0.93680
● Cia Kub: +15C txog +30C
● Solubility.:Aqueous Acid (me ntsis), DMSO (me ntsis, Rhaub, Sonicated), Methanol (me ntsis,
● Dej Solubility.: Soluble hauv dej kub
● XLogP3:-1.1
● Hydrogen Bond Donor Count: 2
● Hydrogen Bond Txais Tus Nqi: 2
● Rotatable Bond suav: 0
● Exact Mass: 112.027277375
● Heavy Atom suav: 8
● Kev nyuaj: 161
Purity/Quality
99%, * cov ntaub ntawv los ntawm cov khoom siv raw
Uracil * cov ntaub ntawv los ntawm cov neeg muab khoom reagent
Cov ntaub ntawv nyab xeeb
● Daim duab:
Xi
● Hazard Codes:Xi
● Cov Lus Qhia Txog Kev Nyab Xeeb: 22-24/25
MSDS Cov ntaub ntawv
Pab tau
● Chemical Classes: Biological Agents -> Nucleic Acids thiab Derivatives
● Canonical SMILES: C1=CNC(=O)NC1=O
● Tsis ntev los no ClinicalTrials: Kawm txog 0.1% Uracil Topical Cream (UTC) rau kev tiv thaiv ntawm tes-foot Syndrome
● Tsis ntev los no EU Clinical Trials: Onderzoek naar de farmacokinetiek van uracil thiab orale toediening bij pati?nten met colorectaal carcinoom.
● Tsis ntev los no NIPH Clinical Trials: Ib theem II sim ntawm uracil ointment rau kev tiv thaiv ntawm capecitabine induced hand-foot syndrome (HFS): .
● Siv: Rau kev tshawb fawb biochemical, tshuaj synthesis;siv los ua cov tshuaj intermediates, kuj siv hauv cov organic synthesis Nitrogenous puag ntawm RNA nucleosides.antineoplastic hauv kev tshawb fawb biochemical.Uracil (Lamivudine EP Impurity F) yog lub hauv paus nitrogenous ntawm RNA nucleosides.
● Nqe lus piav qhia: Uracil yog pyrimidine puag thiab ib qho tseem ceeb ntawm RNA uas nws khi rau adenine ntawm hydrogen bonds.Nws tau hloov mus rau hauv nucleoside uridine los ntawm kev sib ntxiv ntawm ribose moiety, ces mus rau nucleotide uridine monophosphate los ntawm kev sib ntxiv ntawm ib pab pawg phosphate.
